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management rheumatology symptoms differential antimda5 antimda5dm autoimmune behcet buffalohump clinical cushings dermatology dermatomyositis disease gca giantcell gravis moonfacies myasthenia myopathy
CREST Syndrome: Pathogenesis and Clinical Findings CALCINOSIS (BB-sized, hard nodules in fingers) RAYNAUD'S Phenomenon ESOPHAGEAL DYSMOTILITY SCLERODACTYLY (thickening and tightening
CREST Syndrome: ... tightening of skin ... TELANGIECTASIA (In face, hands ... distal to MTPs) #CREST ... #Diagnosis #Signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... injury) • Neurologic ... test (this is a skin ... inhibitors • Uveitis- Ophthalmology ... #signs #symptoms
Cushing's Syndrome - Moon Facies, Buffalo Hump, Abdominal Striae, Thin Skin A young man presents with rapid
Cushing's Syndrome ... Abdominal Striae, Thin Skin ... the patient's hand ... Next diagnostic ... #Signs #MoonFacies
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
or the anterior chest ... fingertips ("mechanic’s hands ... • Arthralgia/arthritis ... • Mechanic's hands ... #dermatology #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... , neurologic, and ... cognitive impairment, neurologic ... occasional oligoclonal bands
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... variably: On one hand ... required due to skip ... required +/- prompt ophthalmology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
, rheumatoid arthritis ... test - Cogan sign ... - Peek sign ... Imaging - CT Chest ... #management #neurology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... dyspnea, cough, chest ... Extrapulmonary: ankle arthritis ... nodes: 13-15%, skin ... #Management #Signs
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... Gottron sign) ... • Shawl sign • ... • Nonerosive arthritis ... • Mechanic's hands
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