31 results
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... basement membrane disease ... hematuria • Signs ... of glomerular disease ... #causes #urology
Cushing's Syndrome - Moon Facies, Buffalo Hump, Abdominal Striae, Thin Skin

A young man presents with rapid
Cushing's Syndrome ... Abdominal Striae, Thin Skin ... the patient's hand ... Next diagnostic ... #Signs #MoonFacies
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... injury) • Neurologic ... test (this is a skin ... inhibitors • Uveitis- Ophthalmology ... #signs #symptoms
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Chorioretinitis • Diagnosis ... - Compatible syndrome ... , may also see skin ... #causes #radiology ... #neurology
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
wane; diagnosis ... trauma leads to skin ... painless, no systemic signs ... Infection #clinical #photo ... #hand
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... the palms of the hands ... resembling rashes caused ... #Clinical #Photo
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... (AQP4-lgG disease ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Carpal Tunnel Syndrome ... • Enlarged hands ... Cardiovascular disease ... #signs #symptoms
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... fingertips ("mechanic’s hands ... severity of the disease ... • Mechanic's hands ... #dermatology #diagnosis
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Differential Diagnosis ... signs of end-organ ... renal bruit or signs ... Renal parenchymal disease ... Neurologic disorders