6 results
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
CREST Syndrome: ... tightening of skin ... TELANGIECTASIA (In face, hands ... distal to MTPs) #CREST ... #Diagnosis #Signs
Cushing's Syndrome - Moon Facies, Buffalo Hump, Abdominal Striae, Thin Skin

A young man presents with rapid
Cushing's Syndrome ... Abdominal Striae, Thin Skin ... the patient's hand ... Next diagnostic ... #Signs #MoonFacies
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... injury) • Neurologic ... test (this is a skin ... inhibitors • Uveitis- Ophthalmology ... #signs #symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... , neurologic, and ... cognitive impairment, neurologic ... occasional oligoclonal bands
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... variably: On one hand ... required due to skip ... required +/- prompt ophthalmology
Terry's Nails

Patient of about 70 years, HIV positive, transplanted kidney donor cadaver in the previous 6
in addition to signs ... skin stretch marks ... such as nephrotic syndrome ... #Hands #PhysicalExam ... #Clinical #Photo