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hematology differential management anemia classification product reactions agglutinin aplastic clinical cold conditions cryoglobulinemia cryoglobulins dermatology disease eschar extrarticular hemolytic joint
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: HCV infection, ... HBV infection, ... HIV infection ... Henoch-Schönlein purpura) • Cutaneous ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
to exclude are infections ... strong sign of cutaneous ... pulses, bruis, or blood ... Large Vessel: Blood ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... pulses, bruits, or blood ... HTN • Check: HBV ... #Rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... presentation) • Cutaneous ... Immunoglobulin M (IgM) • Blood ... Mycoplasma, EBV, HIV ... sensitize red blood
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... Idiopathic • Infections ... , eosinophilic fasciitis ... result from low blood ... #diagnosis #management
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... hyphae invading blood ... Indiana University Infectious ... #dermatology #skin ... #clinical #photo
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
include: fever, cutaneous ... Infection - Infection ... with skin flora ... #Transfusion #diagnosis ... #management #hematology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Lyme disease, Vasculitis ... arteritis • Bloody ... • Eosinophilic fasciitis ... #differential #diagnosis ... #rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
include: fever, cutaneous ... • Infection - ... with skin flora ... #Transfusions #diagnosis ... #management #hematology
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