11 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... Injury (DILI) ... Viral Hepatitis ... #Hepatology #gastroenterology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... IU/mL and ALT > ULN ... injury (INR > 2 ... mg/dL) or acute liver ... Indications #management #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... Congenital, Others, Cirrhosis ... Ducts - CBD ... #diagnosis #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
and Management Algorithm ... viremia or have cirrhosis ... #HBV #Algorithm ... Diagnosis #Management #Treatment ... #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... Check Acute viral hepatitis ... : < 1 • Cirrhosis ... #differential #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... : < 1 • Cirrhosis ... #injury #hepatitis ... #hepatology
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
unresponsive to treatment ... • Elevated liver ... autoimmune thyroiditis, hepatitis ... Inflammatory (IBD ... #gastroenterology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... injury, though ... regarding need for treatment ... Diagnosis #Management #Hepatology