8 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... : INR/PT, aPTT(liver ... #Differential # ... #Workup #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... AST/ALT (5-10x ULN ... infiltration) Differential ... Diagnosis: Viral ... #Pregnancy #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... • ALP > 1.5 x ULN ... or higher • Liver ... bile ducts Differential ... #workup #hepatology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
decompensated liver ... Inherited Urea Cycle Disorders ... Reye syndrome (Peds ... Hyperammonemia #Differential ... #Diagnosis
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
Hypertensive Disorders ... pits <100k), ↑ liver ... enzymes (2x ULN ... hemolysis, elevated liver ... obstetrics #cardiology #differential
Pyogenic liver abscess in children
Common bacterial causes in children:
 • S.aureus
 • Strep spp
 • Enteric
Pyogenic liver abscess ... #abscess #pediatrics ... #children #peds ... #differential # ... diagnosis #hepatology
Causes of Failure to Thrive - Differential Diagnosis Algorithm
Adequate Calorie Consumption
 - Increased Losses:
Diagnosis Algorithm ... Disease • Liver ... • Metabolic Disorders ... #Causes #Peds # ... Pediatrics
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Connective tissue disorders ... Sarcoidosis) • Liver ... Gap #ProteinGap #differential ... #diagnosis #hematology