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Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
Modified Hyponatremia ... Algorithm Hypertonic Hyponatremia ... irrigants Hypotonic Hyponatremia ... - RAAS ON (UNa ... - RAAS OFF (UNa
Causes of Hyponatremia - Differential Diagnosis Algorithm Hypovolemia, UNa > 20: • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Hypovolemia, UNa ... Hypovolemia, UNa ... Hypervolemia, UNa ... Cardiac failure #Hyponatremia
Hyponatremia Diagnosis Algorithm UOsm ≥ POsm - Vasopressin-Dependent • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis ... Vasopressin-Dependent • UNa ... Cirrhosis • UNa ... @NephroMD #hyponatremia
Hyponatremia - Diagnostic Evaluation Algorithm Step 1: Consider whether Posm may actually be normal or elevated Step 2:
Hyponatremia - Diagnostic ... status and measure UNa ... DrEricStrong #Hyponatremia
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
Approach to Hypotonic Hyponatremia ... case of hypotonic hyponatremia ... or Ineffective (UNa ... solute intake, UNa ... Physiologic #Hypotonic #Hyponatremia
Visualizing Hypotonic Hyponatremia • UNa reveals RAAS activity. • UOsm reveals ADH activity. • ADH secretion
Visualizing Hypotonic Hyponatremia ... • UNa reveals ... #Hypotonic #Hyponatremia
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... Vasopressin-dependent - UNa ... following HSCT) - UNa ... metastases) #Hyponatremia
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
Hyponatremia (<135 ... True hyponatremia ... concentration (UNa ... intravascular volume; UNa ... SIADH #Thiazides #UNAa
Management of SIADH Treat underlying cause: • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
• With lower Na ... osmolality < 538 AND UNa ... SIADH #Management #hyponatremia
SIADH Treatment Options 1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
• With lower Na ... osmolality < 538 AND UNa ... Re-check the serum Na ... SIADH #Management #hyponatremia
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