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hyponatremia differential low management treatment cancer hypotonic oncology physiologic table volume
Hyponatremia Diagnosis Algorithm UOsm ≥ POsm - Vasopressin-Dependent • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis ... Algorithm UOsm ... Cirrhosis • UNa ... Inappropriate - Consider: SIADH ... #causes #nephrology
Management of SIADH Treat underlying cause: • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... pain, primary lung ... promoting passive sodium ... SatyaPatelMD #SIADH ... #hyponatremia #nephrology
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
- RAAS ON (UNa ... - RAAS OFF (UNa ... > 30): SIADH, Medications ... #diagnosis #sodium ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... or Ineffective (UNa ... #differential #diagnosis ... #nephrology
SIADH Treatment Options 1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... Primary lung pathology ... administered • This can cause ... promoting passive sodium ... #hyponatremia #nephrology
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
Algorithm Hypovolemic ... treat underlying cause ... , SSRIs) - SIADH ... #Algorithm #diagnosis ... #nephrology #sodium
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
acid >4 • Urine Na ... uric acid <4 • SIADH ... #Hyponatremia #algorithm ... #diagnosis #sodium ... #low #nephrology
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
- Differential Algorithm ... • Euvolemia: SIADH ... #Differential #Algorithm ... #diagnosis #causes ... #nephrology #sodium
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Algorithm in Cancer ... inappropriate • SIAD ... tumors, brain or lung ... chemotherapy, nausea ... #nephrology #oncology
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