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nephrology differential management table algorithm causes comparison ebv hypotonic hypovolemia osmolality pathophysiology physiologic potomania saltwasting thiazides unaa
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
ON (UNa < 30): ... SIADH, Medications ... Reset osmostat, Cerebral ... #Algorithm #diagnosis ... #sodium #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
RAAS Inactive ... or Ineffective (UNa ... (Uosm ≥100): SIADH ... Insufficiency, Cerebral ... #differential #diagnosis
Cerebral Salt Wasting vs SIADH - Pathophysiology 1) Neurological event 2) Sodium loss from tubules 3) Naturiesis →
Neurological event 2) Sodium ... Hypovolaemia → ADH ... reabsorption 5) ↓ Na ... Pathophysiology #diagnosis ... #nephrology #hyponatremia
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
Diagnosis by Mechanism ... secretion (SIADH ... carcinoma of the lung ... osmostat - Cerebral ... Table #Causes #Sodium
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
consequence of cerebral ... concentration (UNa ... #hyponatremia #ADH ... EBV #potomania #SIADH ... #Thiazides #UNAa
Management of SIADH Treat underlying cause: • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
pain, primary lung ... promoting passive sodium ... osmolality < 538 AND UNa ... antagonists: • Blocks ADH ... #nephrology #treatment
SIADH Treatment Options 1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... Pain, Primary lung ... promoting passive sodium ... vaptans) • Blocks ADH ... #Management #hyponatremia
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