6 results
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
: • ADH ON (UOsm ... > 30): SIADH, Medications ... Reset osmostat, Cerebral ... #Algorithm #diagnosis ... #sodium #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
(Uosm ≥100): SIADH ... , Renal Sodium loss ... Insufficiency, Cerebral ... #differential #diagnosis ... #table #sodium
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) Sodium ... Hypovolaemia → ADH ... reabsorption 5) ↓ Na ... Pathophysiology #diagnosis ... #nephrology #hyponatremia
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
secretion (SIADH ... carcinoma of the lung ... osmostat - Cerebral ... #Table #Causes ... #Sodium
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
pain, primary lung ... promoting passive sodium ... osmolality < 538 AND UNa ... antagonists: • Blocks ADH ... #nephrology #treatment
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... Pain, Primary lung ... promoting passive sodium ... vaptans) • Blocks ADH ... #Management #hyponatremia