6 results
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
- RAAS ON (UNa ... < 30): Hypovolemia ... - RAAS OFF (UNa ... > 30): SIADH, Medications ... Reset osmostat, Cerebral
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
or Ineffective (UNa ... (Uosm ≥100): SIADH ... , Renal Sodium loss ... Insufficiency, Cerebral ... solute intake, UNa
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Cerebral Salt Wasting ... Neurological event 2) Sodium ... → ADH → water reabsorption ... 5) ↓ Na+ → Subclinical ... diagnosis #nephrology #hyponatremia
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
consequence of cerebral ... concentration (UNa ... intravascular volume; UNa ... #hyponatremia #ADH ... #Thiazides #UNAa
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
pain, primary lung ... promoting passive sodium ... osmolality < 538 AND UNa ... antagonists: • Blocks ADH ... #nephrology #treatment
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... Pain, Primary lung ... promoting passive sodium ... osmolality < 538 AND UNa ... vaptans) • Blocks ADH