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diagnosis causes algorithm management comparison pharmacology clinical cardiology nephrology radiology pulmonary neurology medications hematology dermatology classification pediatrics endocrinology workup infections
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
• ADH Present (Uosm ... be high or low Uosm ... • ADH Present (Uosm ... #Hyponatremia #differential ... #diagnosis #table
Hyponatremia Diagnosis Algorithm UOsm ≥ POsm - Vasopressin-Dependent • UNa < 20 mEq/L - Appropriate (↓ EABV)
Diagnosis Algorithm UOsm ... ≥ POsm - Vasopressin-Dependent ... Cortisol deficiency UOsm ... < POsm - Vasopressin-independent ... hyponatremia #diagnosis #differential
Polyuria - Differential Diagnosis Algorithm Urine Output > 3L /day Water Diuresis (Urine Osm <100 mOsm/kg) • Primary
Polyuria - Differential ... Diuresis (Urine Osm ... <100 mOsm/kg) ... 100-200 mOsm/kg ... #Polyuria #Differential
Hypo-osmolar Hypotonic HypoNatremia Algorithm (Serum Na+ < 135 meq/L, serum Osm < 275 mosm/kg) Assess Volume Status,
135 meq/L, serum Osm ... < 275 mosm/kg) ... Urine Na, Urine Osm ... Diagnosis #Nephrology #Differential
Hyponatremia Differential Diagnosis Table • Step 1: Correct for hyperglycemia. Corrected Na = [(glucose - 100)/
Hyponatremia Differential ... Diagnosis Table ... • Urine Osm ... #Hyponatremia #Differential ... #Diagnosis #Table
Pathophysiology Based Approach to Hyponatremia - Diagnostic Algorithm Not the "classic" Volume based approach. #Hyponatremia #Algorithm #Pathophysiology
Pathophysiology #Diagnosis #Differential ... #Nephrology #UOsm
Urine chemistry tests for the diagnostic evaluation of a patient with polyuria UOsm <100 mOsm/Kg (H2O diuresis)
with polyuria UOsm ... nephrogenic) UOsm ... 2 × (Na + K) = UOsm ... #polyuria #differential ... diagnosis #nephrology #Uosm
Hyponatremia - Diagnostic Evaluation Algorithm Step 1: Consider whether Posm may actually be normal or elevated Step 2:
Consider whether Posm ... Step 2: Check Uosm
Central vs Nephrogenic Diabetes Insipidus - Desmopressin Challenge Give desmopressin (intranasal, SQ, IV) and monitor UOsm every
IV) and monitor UOsm ... • No Rise in UOsm ... < 45% rise in UOsm ... 15-50% rise in UOsm ... CDI • Rise in UOsm
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... ) Euvolemic • UOsm ... Toast Diet • UOsm ... #Hyponatremia #Differential
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