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management hematology differential neurology oncology acidosis classification dermatology elevation encephalopathy gravis lactate lactic leukemia mds myasthenia myelodysplastic nephrology nonpalpable palpable
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute ... #hematology #oncology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis ... normal in mild cases ... - Acute Bleeding ... Avoid meds that ... #treatment #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... Liver disease • Hemophilia ... - APLS • Acute ... #hematology #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
muscles: “myasthenic crises ... myasthenia Diagnosis ... Myasthenia Crises ... aspiration and acute ... Myasthenia #Gravis #diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
• Hypertensive crisis ... , ADEM, Acute toxic ... the underlying cause ... • Treatment of ... until cause identified
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
: 1) Acute kidney ... microangiopathic hemolytic anemia ... , add other BP meds ... • Refractory cases ... #rheumatology #
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
before beginning treatment ... cardiac output - Acute ... - Compartment syndrome ... peritonitis - Acute ... 30mmHg) - Severe anemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Oncology #Diagnosis
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