13 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... l MD SOAP) - Risks ... PT, aPTT(liver disease ... changes), high MCV anemia ... #Workup #hematology
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Sickle-cell disease ... recessive blood disorder ... Crises can be precipitated ... Sickle cell disease ... 2) Aplasia - Acute
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Blood Loss • Acute ... Disease • Marrow ... • RBC Membrane Disorder ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Infectious: • Acute ... • Rheumatic disorders ... • Celiac disease ... Iron deficiency anemia ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... - Hemolytic anemia ... Von Willebrand disease ... - APLS • Acute ... #rheumatology #
Blurry Vision - Differential Diagnosis Framework

Anatomical Approach to Eye Disease:
1. Lids/Lashes
2. Extraocular Muscles/Motility
3. Conjunctiva/Sclera
4. Cornea
5. Anterior
Approach to Eye Disease ... • Ulcer • Iritis ... • Migraine • Acute ... retinopathy (sickle cell anemia ... ophthalmology #causes
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Myeloproliferative Disease ... Neutropenia • Platelet Disorders ... Workup: • Complete
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Screening Tests for Acute ... metabolic or endocrine disorders ... Arthritis #laboratory #workup
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
cells can indicate disease ... lymphoproliferative disorders ... • Neutropenia, anemia ... ’s lymphoma or acute ... Leukemia #diagnosis #workup
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
: 1) Acute kidney ... microangiopathic hemolytic anemia ... , add other BP meds ... • Refractory cases ... #rheumatology #