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diagnosis anemia differential management oncology agglutinin aplastic classification cold disease gap globulin hemolytic hodgkins lymphoma myopathy myositis protein proteingap thresholds
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
NEJM 1999 - ICU FOCUS ... Blood saves lives ... unnecessary and cause ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... Viral Infection Clinical ... Blood smear - RBC ... - Mycoplasma, EBV ... hemolytic #anemia #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... Pancytopenia: • ↓ RBC ... may result from low ... Anemia #oncology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
acute HIV, HBV, EBV ... Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... gastric tumors • Hematology ... differential #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... • History of EBV ... Immunosuppression • Autoimmune ... Hodgkin Lymphoma - Clinical ... classification #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... • ANA < 20 % IBM ... statins - probably caused ... Other Diseases: • PBC ... Myositis #Myopathy #rheumatology
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