11 results
Bilateral B-Lines in case of Pneumonia on Lung POCUS

Young healthy pt with fever/dyspnea. POCUS lung exam
in case of Pneumonia ... Progressive URI ... interstitial lung disease ... RJonesSonoEM #BLines ... #clinical #ultrasound
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... - Clinical Presentation ... (90-95% of cases ... number of sites of disease ... classification #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... , B-cell lymphoma ... Drugs, Unknown cause ... treatment #summary #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... hepatitis • Lymphoma ... • Nodules • Lymphoid ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... Blood saves lives ... unnecessary and cause ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
originate from a low-grade ... - Monoclonal - Lymphoid ... Viral Infection Clinical ... - Mycoplasma, EBV ... hemolytic #anemia #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Non-autoimmune rheumatologic ... Angioimmunoblastic T-cell lymphoma ... vein thrombosis Hematologic ... Erythematosus #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... Biologic: 2nd or 3rd line ... Sjogrens #Syndrome #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Amyloidosis • Lymphoma ... acute HIV, HBV, EBV ... gastric tumors • Hematology ... : Lymphoma, Leukemia ... differential #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... • Cytopenia -> BM ... -> AML: Blast crises ... response to mosquito bites ... #Leukemia #Hematology