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diagnosis differential oncology anemia aplastic autoimmune gap globulin leukemia management myopathy myositis protein proteingap thresholds transfusion trials visualabstract
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
NEJM 1999 - ICU FOCUS ... Blood saves lives ... unnecessary and cause ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... Constitutional Syndromes ... Pancytopenia: • ↓ RBC ... Anemia #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... response to mosquito bites ... #Leukemia #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... acute HIV, HBV, EBV ... autoimmune hepatitis, PBC ... gastric tumors • Hematology ... differential #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... • ANA < 20 % IBM ... statins - probably caused ... Other Diseases: • PBC ... Myositis #Myopathy #rheumatology
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