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diagnosis management lupus summary syndrome comparison dermatology erythematosus hemophagocytic hlh leukemia lymphohistiocytosis oncology sapho sjogrens systemic table tafro thrombocytopenia
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
, SCLE-DIL (terbinafine ... constitutional symptoms • Treatment ... life-threatening • Treatment ... Lupusreference #druginduced ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... versus DIL • ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
, SCLE-DIL (terbinafine ... Discontinuation of causal ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology ... #diagnosis #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Fibrinogen level, ↑ sIL ... Autoimmune diseases: SLE ... Treatment: • ... diagnosis #management #treatment ... #summary #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammation of the bones ... Rule out other causes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Fibrinolysis & DIC ... lymphocytic lymphoma (SLL ... response to mosquito bites ... #Leukemia #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... • Nephrogenic DI ... Hematologic: ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
erythematosus (SLE ... with interleukin (IL ... Hypoalbuminemia Treatment ... high dose - 2nd line ... diagnosis #management #rheumatology
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