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management hematology bilateral coagulation dic disseminated hemeonc hemophagocytic hit hlh induced intravascular lung lymphohistiocytosis pneumonia polychondritis relapsing sjogrens summary syndrome
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Pathophysiology: • IgG binds ... Clinical Suspicion ... Confirmatory test ↑Se ... A/C if clinical ... #Treatment #Hematology
Bilateral B-Lines in case of Pneumonia on Lung POCUS Young healthy pt with fever/dyspnea. POCUS lung exam
in case of Pneumonia ... travel hx, home meds ... Progressive URI ... NOT definitively diagnose ... #clinical #ultrasound
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 Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... + Bleeding Treatment ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... +++ (Plt, Hb), Hepatic ... Autoimmune diseases: SLE ... Treatment: • ... #summary #rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
erythematosus (SLE ... syndrome - IGG4 - Hepatic ... Histopathological Diagnoses ... Hypoalbuminemia Treatment ... #management #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... such as: • SLE ... : • Clinical tests ... affected tissue Treatment ... Polychondritis #rheumatology
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