31 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... hydroxide • Hyperkalemia ... - Standard treatment ... #TumorLysis #Syndrome
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... Typical ECG ... ) BRASH Treatment ... • Aggressive treatment ... DrEricStrong #BRASH #Syndrome
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... • Consider K+ binder ... potassium and ECG ... , asystole #hyperkalemia ... management #algorithm #treatment
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... with Ca only if EKG ... #Tumor #Lysis #Syndrome ... #TLS #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... leukapheresis - TLS ... hydration - Hyperkalemia ... unless worrisome EKG ... #TLS #diagnosis
Approach to ECGs - Tachy/Bradyarrhythmias
Tachyarrhythmias - HR > 100
Wide
  (1) VT - DANGER
  (2)
B Afib + WPW - DANGER ... 3 different P waves ... (2) Sick Sinus Syndrome ... bradyarrhythmia #ECG ... #EKG #diagnosis
Causes of ST Segment Elevation - Differential Diagnosis Framework

STEMI:
 • Upsloping convex STE: "Pardee's sign" +
Syndromes • Early ... involved • Brugada Syndrome ... Disorders: • Hyperkalemia ... • Hypercalcemia ... #ekg #electrocardiogram
Wolff-Parkinson-White Syndrome

WPW is a congenital abnormality characterized by an abnormal accessory conduction pathway between the atria
Wolff-Parkinson-White Syndrome ... out for a delta wave ... The definitive treatment ... complex (Delta wave ... #EKG #Electrocardiogram
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hyporeflexia: • Hypercalcemia ... polyneuropathy (e.g ... Guillain-Barré syndrome ... injury, Early ALS ... Hyperthyroidism, Serotonin syndrome
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... HIV, Influenza, TSS ... or compartment syndrome ... Treatment of underlying ... fluid/Lactated ringers