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differential hematology management signs oncology arthritis leukemia cll erythematosus lupus lymphocytic pain ra rheumatoid sle systemic vasculitis workup abdominal algorithm
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Tunnel, Sicca Syndrome ... and ILD Complications ... Arthritis #RA #diagnosis ... #rheumatology # ... signs #symptoms
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
- Differential Diagnosis ... did not yield a diagnosis ... changes • Urinary symptoms ... • Budd-Chiari syndrome ... Abdominal cutaneous nerve
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Polyneuropathy, Cranial nerve ... Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... Recurrent and chronic ... #signs #symptoms ... #rheumatology #
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
noninfectious complications ... Autoimmunity • Chronic ... : • Nephrotic syndrome ... Malignancies • Chronic ... (Epstein-Barr syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... phenomenon CLL Diagnosis ... cells can indicate disease ... • Richter’s Syndrome
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... thrombocytopenia Complications ... chemotherapy for low-risk disease ... #hemeonc #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Transformation: • Complication ... #Oncology #Diagnosis
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
severe clinical complications ... Malnutrition due to chronic ... disease/malabsorptive ... overload) Other Symptoms ... #Differential #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Eosinophilia, asthma, chronic ... and peripheral nerves ... Presentation - Systemic Symptoms ... #rheumatology #
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