6 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... Hypokalemia Metabolic alkalosis ... #Syndrome #Pathophysiology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... ratio 0.5%) Differential ... Supplement: • Potassium ... #nephrology #management ... #pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... of sodium and potassium ... urine #Algorithm #nephrology ... #differential #
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
: Differential Diagnosis ... furosemide-like lesion) • Gitelman ... other • Severe potassium ... #Differential # ... Diagnosis #Causes #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis
Chloride depletion syndromes
 • Gastrointestinal losses
    -
Causes of Metabolic Alkalosis ... - Differential ... Diagnosis Chloride ... - Gitelman ... #Differential #
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... - Metabolic Alkalosis ... , Gitelman syndrome ... diagnosis #Algorithm #differential ... #potassium #nephrology