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vasculitis cryoglobulinemia hypersensitivity reactions allergic cryoglobulins definitions differential erythematosus lupus management pathophysiology sjogrens sle systemic vasculitides
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
Diagnosis of Cryoglobulinemia ... Hyperviscosity syndrome ... • Arthralgia, arthritis ... #Vasculitis #Diagnosis ... #Rheumatology #
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
conjunctivitis Type ... Erythematosus, Reactive Arthritis ... Stevens-Johnson Syndrome ... #Types #Classification ... #Diagnosis #Definitions
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- type II cryoglobulinemia ... arthralgia, and arthritis ... Labs/Diagnosis: ... #types #classification ... #rheumatology #
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
When the specific allergen ... glomerulonephritis, rheumatoid arthritis ... #Classification ... #Diagnosis #Reactions ... #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... ANCA +MPO) • Cryoglobulinemic ... Low levels mixed cryoglobulinemia ... #rheumatology # ... classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Differential Diagnosis ... Kikuchi disease • Type-I ... pain • Swan neck/Ulnar ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... IV RTA, TYPE I ... Vasculitis: • 7%, Cryoglobulinemia ... Arthralgia and Arthritis ... #Rheumatology #
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