9 results
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
with temporal arteritis ... /or joint aches ... ) VA Joint Chiefs ... #differential # ... diagnosis #comparison #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
present both at rest ... e.g., congenital hip ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
- parvovirus, HIV ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
nociceptors -> Pain with rest ... in Rheumatoid arthritis ... affects the knee hip ... > Stiffness is short-lived ... Comparison #Versus #MSK
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... spine, shoulders, hips ... Joint #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... : HIV test, a rubella ... #laboratory #workup ... diagnosis #testing #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... : • Joint pain ... • Swan neck/Ulnar ... arthropathy • 90% joints
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... vesicular eruption - Joints ... retinopathy Lab Tests ... Cryoglobulins • HIV ... #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Diagnostic Tests ... Syndrome: Fever, joint ... weakness + atrophy- Hip ... • Nonerosive arthritis ... • Mechanic's hands