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growthhormone management radiology symptoms xray acromegaly comatose excess feedbackloop fracture fractures hand msk neurology orthopedics overproduction physicalexam pituitary ra rheumatoidarthritis
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
overgrowth: • Carpal ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology ... #pathophysiology
Triquetral Fracture The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
"pooping duck sign ... "pooping duck sign ... distal to distal ulna ... , pain with wrist ... #XRay #Diagnosis
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... malignancy Pathophysiology ... Differential Diagnosis ... #Management #Endocrinology ... #Treatment #Pathophysiology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
small joints (wrists ... boggy" joints, esp carpal ... Boutonniere's ulnar ... RheumatoidArthritis #RA #pathophysiology ... #diagnosis
Common Hand Fractures on X-Ray Mallet finger - injury to the lateral extensor slips Boutonniere deformity - injury
thumb injury to ulnar ... Terry thomas sign ... XRay #Radiology #Wrist ... #differential # ... diagnosis
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... Diagnosis: • ... • Mutism Pathophysiology ... • Examine for signs ... neurology #comatose #diagnosis
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