6 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
overgrowth: • Carpal ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology ... #pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
: Commonly no signs ... Bone/joint pain Psychiatric ... Hyperparathyroidism #diagnosis ... #endocrinology ... Secondary #Tertiary #pathophysiology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
boggy" joints, esp carpal ... Boutonniere's ulnar ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms ... #diagnosis
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
having a small waist ... AnorexiaNervosa #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
Bulimia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: Some
having a small waist ... BulimiaNervosa #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry