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rheumatology signs chondrocalcinosis pseudogout alkaline arthritis comparison differential hand hepatology hyophosphatasia inflammatory low patterns phosphatase rheumatoidarthritis vasculitis
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... joints (shoulders, wrists ... • Underlying disease ... states Pathophysiology ... Arthritis: Resembles RA
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Pathogenesis and Joint diseases ... Boutonniere's ulnar ... #pathophysiology ... #signs #symptoms ... #diagnosis
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
produced, incr gut ... - CPPD Crystals ... #Disease #Signs ... #Symptoms #Pathophysiology ... #Diagnosis
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
) Deposition Disease ... ) (tends to be out ... affected — e.g., wrist ... #Symptoms #Pathophysiology ... #Diagnosis
Arthritis of the Hand - Arthritis Patterns Osteoarthritis: • Osteoarthritis of the hand usually involves the DIP and
nodes - DIP • XRAY ... subluxation causing ulnar ... = RA • 2nd & 3rd ... Polyarticular gout ... patterns #hand #diagnosis
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
nephrocalcinosis • CPPD ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... mineralization Symptoms ... fractures • Dental
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... claudication, visual ... • Progressive symptoms ... purpura, joint & gut ... , Elevated AST ALT
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