7 results
Triquetral Fracture
The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
distal to distal ulna ... , pain with wrist ... distal radius or ulna ... #Wrist #Carpal ... #Diagnosis #Management
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
> Clearance of calcium ... (CPPD) crystals ... mineralization of calcium ... Signs #Symptoms #Pathophysiology ... #Diagnosis
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pathophysiology ... culture used to diagnose ... #Calcium #Pyrophosphate ... Deposition #Disease #Rheumatology ... #diagnosis #management
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... : • Pyrophosphate ... precipitates with calcium ... Gout #Comparison #rheumatology ... #Diagnosis
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
Chondrocalcinosis: Calcium ... Pyrophosphate Dihydrate ... affected — e.g., wrist ... Signs #Symptoms #Pathophysiology ... #Diagnosis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Swelling notable on Xray ... boggy" joints, esp carpal ... Boutonniere's ulnar ... RheumatoidArthritis #RA #pathophysiology ... signs #symptoms #diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• recurrent fractures ... nephrocalcinosis • CPPD ... • Inorganic pyrophosphate ... collection with EDTA Pathophysiology ... ALP -> PPi and Calcium