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management druginduced syndrome amyloid amyloidosis comparison disease erythematosus hand hematology inflammatory laboratory macrophage mas patterns rheumatic rheumatoid sjogrens systemic table
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... Constitutional symptoms, Arthritis ... , SCLE-DIL (terbinafine ... #table #rheumatology ... #diagnosis #management
Arthritis of the Hand - Arthritis Patterns Osteoarthritis: • Osteoarthritis of the hand usually involves the DIP and
subluxation causing ulnar ... deviation • SLE ... • MCP + PIP + Wrist ... patterns #hand #diagnosis ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... erythematosus [SLE ... Liver function tests ... #Syndrome #Diagnosis ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... pain • Swan neck/Ulnar ... Chronic B-cell activation ... #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... (to support a diagnosis ... ANA and RF (if clinical ... #testing #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... , SCLE-DIL (terbinafine ... #DIL #rheumatology ... #diagnosis #treatment
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
osteomyelitis, Rheumatoid arthritis ... Clinical suspicion ... arthropathy • Carpal ... Inflammation → Macrophage activation ... → IL-1 & IL-6 →
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... Sjogrens #Syndrome #Rheumatology
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