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symptoms management differential erythematosus hematology lupus sle activation antimda5dm arteritis autoimmune behcet chronic classification cll dermatology dermatomyositis disease gca giantcell
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of hip (rare), Arthritis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... association • M > F Clinical ... (Clinical Dx). ... #signs #symptoms ... #rheumatology #
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis ... boggy" joints, esp carpal ... Boutonniere's ulnar ... deviation, etc • Systemic ... #symptoms #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
auricular papules Clinical ... -74%] • Blood tests ... • Arthralgia/arthritis ... #rheumatology # ... dermatology #diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... signs/sx of inflammation ... the “Chewing gum test ... them, but urgent rheumatology ... GCA #Temporal #Signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Clinical Features ... pain • Swan neck/Ulnar ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... • Cogan Syndrome ... purpura: strong sign ... retinopathy Lab Tests ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... adults in the west ... Orange or Hep C Clinical ... Physical Exam/Signs ... ’s CLL Scoring system
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tests: • Measure ... papules and Gottron sign ... ) • Shawl sign ... • Nonerosive arthritis ... • Conduction system
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