9 results
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Rheumatoid arthritis ... , esp carpal, MCP ... Boutonniere's ulnar ... fingers, radial wrist ... deviation, etc • Systemic
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
spondyloarthropathies, lupus ... #rheumatology # ... approach #workup ... #differential # ... diagnosis #arthritis
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
present both at rest ... improves quickly with rest ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... • Systemic lupus ... #laboratory #workup ... diagnosis #testing #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... months to years) Systemic ... sle #comparison #table ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... : • Joint pain ... • Swan neck/Ulnar ... arthropathy • 90% joints
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... especially in the wrists ... the face (many differential ... diagnosis #sle #clues #system ... erythematosus #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... vesicular eruption - Joints ... lupus erythematosus ... retinopathy Lab Tests ... #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Diagnostic Tests ... Syndrome: Fever, joint ... • Nonerosive arthritis ... • Mechanic's hands ... • Conduction system