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diagnosis differential ana antinuclear erythematosus activation autoantibodies autoimmune classification hematology laboratory macrophage management mas myopathy myositis pathophysiology ra rheumatic rheumatoid
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Juvenile Idiopathic Arthritis ... SLE), Sjogren's Syndrome ... #Antinuclear #Antibodies ... #rheumatology #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... SLE), Sjogren's Syndrome ... : Lupus (SLE), Systemic ... , Sjögren Syndrome ... #rheumatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... pain • Swan neck/Ulnar ... 1, SCL-70, RNP antibodies ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... idiopathic arthritis ... lupus erythematosus ... Liver function tests ... #Rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... clinically suspected, tests ... SLE-SSc-AlM overlap syndromes ... #diagnosis #rheumatology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis ... Pathogenesis and Joint diseases ... characteristic antibodies ... boggy" joints, esp carpal ... Boutonniere's ulnar
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
lupus erythematosus ... retinopathy Lab Tests ... - (C-ANCA) pattern ... : antibodies directed ... differential #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... lupus erythematosus ... double-stranded DNA antibodies ... diagnosis #testing #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Diagnostic Tests ... RP-ILD), dermato-rheumatologic ... slow onset and pattern ... • Nonerosive arthritis ... • Conduction system
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