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diagnosis management ana antibodies antinuclear classification cryoglobulinemia cryoglobulins differential erythematosus lupus pathophysiology patterns polychondritis primary relapsing signs systemic types vasculitis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’ ... accompanies other autoimmune ... like rheumatoid arthritis ... (RA) or systemic ... erythematosus (SLE
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... ), Sjogren's Syndrome ... , Sjögren Syndrome ... ANA #patterns #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
or RA - 5 to ... 20% Sjögren's syndrome ... erythematosus (SLE ... , Sjögren's syndrome ... classification #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dermatomyositis, Sjogren ... disease • Non-autoimmune ... rheumatologic diseases ... pain • Swan neck/Ulnar ... Induced Lupus: • Symptoms
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA ... , SLE • Mikulicz ... Arthralgia and Arthritis ... #Syndrome #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... cases such as: • SLE ... • Sjogren’s syndrome ... Diagnosis: • Clinical tests ... Polychondritis #rheumatology
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