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Algorithm and Differential Diagnosis of Hyperbilirubinemia Direct = Conjugated Indirect = Unconjugated #Diagnosis #Jaundice #Hyperbilirubinemia #Differential #Algorithm #Direct
Hyperbilirubinemia Direct = Conjugated ... Indirect = Unconjugated ... Direct #Indirect #Conjugated ... #Unconjugated #
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
Algorithm #Diagnosis #Management ... Direct #Indirect #Conjugated ... #Unconjugated #
Bilirubin Metabolism - Pathophysiology • Conjugated Bilirubin • Unconjugated Bilirubin By Dr. Khushboo Gala @LouLectures #Bilirubin #Metabolism #Pathophysiology
Pathophysiology • Conjugated ... Bilirubin • Unconjugated
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice Unconjugated ... Crigler-Najjar syndrome ... Dubin-Johnson syndrome ... , Rotor syndrome ... #unconjugated #
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Pre-Hepatic - Unconjugated ... • Gilbert's Syndrome ... Crigler-Najjar Syndromes ... II) Hepatic - Conjugated
Causes of Jaundice - Prehepatic, Intrahepatic, Extrahepatic #Diagnosis #Differential #Jaundice #Prehepatic #Intrahepatic #Extrahepatic #Unconjugated #Conjugated ** GrepMed Recommended
#Extrahepatic #Unconjugated ... #Conjugated
Liver Function Tests (LFTs) - Aspartate aminotransferase (AST) - Alanine aminotransferase (ALT) - Alkaline
Bilirubin - Unconjugated ... Indirect) - Conjugated
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Conjugation == Gilbert Syndrome ... hyperbilirubinemia syndrome ... , intermittent unconjugated ... UGT1A1 activity • Unconjugated ... and unconjugated
Biochemistry and Metabolism of Bilirubin Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
→ Biliverdin → Unconjugated ... Conjugation → Conjugated ... common bile duct Unconjugated ... bilirubin, and conjugated
Jaundice - Pathophysiology and Causes - Amy Chung, MD, MSc @AmyChung #Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
#Differential #Unconjugated
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