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diagnosis differential algorithm treatment nephrology pharmacology criticalcare workup neurology checklist cardiology syndrome anesthesiology anesthesia intraoperative pathophysiology pulmonary toxicology gastroenterology hepatology
Bilirubin Metabolism - Pathophysiology • Conjugated Bilirubin • Unconjugated Bilirubin By Dr. Khushboo Gala @LouLectures #Bilirubin #Metabolism #Pathophysiology
Bilirubin Metabolism ... Pathophysiology • Conjugated ... Bilirubin • Unconjugated ... #Bilirubin #Metabolism
Biochemistry and Metabolism of Bilirubin Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
Biochemistry and Metabolism ... → Biliverdin → Unconjugated ... Conjugation → Conjugated ... common bile duct Unconjugated ... #Biochemistry #Metabolism
Causes of Jaundice - Prehepatic, Intrahepatic, Extrahepatic #Diagnosis #Differential #Jaundice #Prehepatic #Intrahepatic #Extrahepatic #Unconjugated #Conjugated ** GrepMed Recommended
Causes of Jaundice ... #Extrahepatic #Unconjugated ... #Conjugated
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
Algorithm #Diagnosis #Management ... Direct #Indirect #Conjugated ... #Unconjugated #
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice Unconjugated ... cholestasis, and some cases ... miscellaneous causes ... #unconjugated # ... differential #causes
Jaundice - Pathophysiology and Causes - Amy Chung, MD, MSc @AmyChung #Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Pathophysiology and Causes ... #Differential #Unconjugated ... #Causes #Diagnosis
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Pre-Hepatic - Unconjugated ... II) Hepatic - Conjugated ... Diagnosis #Algorithm #Causes
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
and Bilirubin Metabolism ... insult Bilirubin metabolism ... cytochromes) • Unconjugated ... MRP2 transports conjugated ... Tests #Laboratory #Metabolism
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
, intermittent unconjugated ... UGT1A1 activity • Unconjugated ... and stress may cause ... an increase in conjugated ... and unconjugated
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Reticulocytes, Increased Unconjugated ... Disorder • RBC Metabolism ... Diagnosis #Algorithm #Causes
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