82 results
Bilirubin Metabolism - Pathophysiology
 • Conjugated Bilirubin
 • Unconjugated Bilirubin

By Dr. Khushboo Gala @LouLectures

#Bilirubin #Metabolism #Pathophysiology
Bilirubin Metabolism ... Pathophysiology • Conjugated ... Bilirubin • Unconjugated ... #Bilirubin #Metabolism
Biochemistry and Metabolism of Bilirubin
Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
Biochemistry and Metabolism ... → Biliverdin → Unconjugated ... Conjugation → Conjugated ... common bile duct Unconjugated ... #Biochemistry #Metabolism
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
and Bilirubin Metabolism ... insult Bilirubin metabolism ... cytochromes) • Unconjugated ... MRP2 transports conjugated ... Tests #Laboratory #Metabolism
An algorithm for the differential diagnosis of palpitations.

Major Categories: Cardiac, Pharmacologic, Metabolic, Psychiatric

#Diagnosis #Palpitations #Differential #Algorithm
Categories: Cardiac, Pharmacologic ... , Metabolic, Psychiatric
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... angioedema) • Metabolism ... amount of hepatic metabolism ... #Indications #Pharmacology
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Warfarin and DOAC Pharmacology ... Bioavailability - Metabolism ... Warfarin #DOAC #Pharmacology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Reticulocytes, Increased Unconjugated ... Disorder • RBC Metabolism
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
#DOAC #NOAC #Metabolism ... #Pharmacology #
Tramadol - Toxicology
Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1
This
people variably metabolize ... into its active metabolite ... codeine ultra-rapid metabolism ... activity as the M1 metabolite ... in poor codeine metabolism
Bile acids are the end products of cholesterol catabolism. Cholic acid and chenodeoxycholic acid are the
of cholesterol catabolism ... livers and are conjugated ... small amounts of unconjugated ... carbohydrate and fat metabolism ... Bile acid metabolism