11 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Cirrhosis • Chronic ... (Drug-induced liver ... Differential #Diagnosis #hepatology ... #transaminitis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... 5-10x normal - Chronic ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... months without treatment ... #ACLF #Acute #Chronic ... #Cirrhosis #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #differential #Hepatology ... #transaminitis
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
HAV immunity; Liver ... elastographv, liver ... • Liver is the ... Diagnosis #Management #Treatment ... #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... non-essential drug/HDS treatments ... dechallenge • Acute or chronic ... e.g. ascites), Chronic ... Diagnosis #Algorithm #hepatology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
• Caused by liver ... portosystemic shunting ... noxious stimuli) TREATMENT ... Initiate empiric treatment ... #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... - Symptoms of chronic ... hepatocellular pattern of liver ... regarding need for treatment ... Diagnosis #Management #Hepatology
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
obvious causes (chronic ... pressure < 15mmHg TREATMENT ... hemodynamics Liver ... diagnosis #management #hepatology
Hepatopulmonary Syndrome - Illness Script
HPS is a pulmonary disorder of chronic liver disease characterized by a
pulmonary disorder of chronic ... triad of: 1) chronic ... arteriovenous shunting ... the left heart TREATMENT ... cirrhosis #diagnosis #hepatology