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diagnosis management signs differential hematology hepatology pathophysiology abnormal arteritis chronic common cvid dermatology enzymes gca giantcell hepatitis histiocytosis hypertensive hypogammaglobulinemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... lineage ALL Symptoms ... crises • Blasts ... Intracellular Urate ... Transformation: • Complication
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Infiltration: Often breast ... CA, small cell ... differential #diagnosis #algorithm
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... in sun exposed areas ... hair follicles -> causes ... diagnosis #signs #symptoms ... #complications
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
white or yellow areas ... around atrophic areas ... pathophysiology #ophthalmology ... diagnosis #signs #symptoms ... #complications
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... suspicious clinical symptoms ... Areas of diagnostic ... Abnormal USS may well ... LFTs #Abnormal #Algorithm
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... noninfectious complications ... disease • Liver ... - gastric and breast ... DDX - Other causes
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... and ophthalmic complications ... required +/- prompt ophthalmology ... Temporal #Signs #Symptoms
Monkeypox What? Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus Viral zoonotic disease that is
disease that is caused ... • Fomites • Live ... of the systemic symptoms ... , and perianal areas ... IgM antibody Complications
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
Incidence: 4–5 cases ... SPECTRUM Common areas ... • Pulmonary Symptoms ... Multisystem (High Risk) Liver ... organs like the liver
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