10 results
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
and multiple spinal ... - Causes progressive ... Increased Jaw Jerk reflex ... cervical and thoracic spine ... #diagnosis #management
Hoffman's sign. Even in this specific case, accompanied by a clonus outline (rhythmic contractions). The median
this specific case ... nerve acts both as ... pathway and the spinal ... #Positive #Abnormal ... #clinical #video
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... Cord Causes: 1 ... reflexes: Areflexia ... UMN Symptoms ... differential #algorithm
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... depressed deep tendon reflexes ... protein with a normal ... Syndrome #diagnosis #management ... #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Spasticity - Reflexes ... Sjogren's • CSF: - Abnormal ... Myelitis #diagnosis #management ... #neurology #differential
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Clinical ... Decreased / Absent Reflexes ... CSF PROTEIN - NORMAL ... of intrathecal spinal ... Syndrome #diagnosis #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
syndromes such as ... Examination: • UMN ... stimulation Clinical ... Progressive MS (Spinal ... sclerosis #diagnosis #management
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Diagnosis: • Based on clinical ... More likely to cause ... - 1st line: Oral ... Sinai Hospital of ... Gravis #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... skeleton-sacroiliac joint and spine ... Diagnosis: • A clinical ... Rule out other causes ... Rheumatology #diagnosis #management
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... remains unknown • Final ... sx overlap with normal ... defibrillator as ... support for patients clinically