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diagnosis differential hypokalemia alkalosis defects epithelial hypochloremia inherited kidney management metabolic tubule urinary urine
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome • Urine Chloride • Urine Ca/Cr ratio Dr. Krithika
Gitelman syndrome ... from Bartter syndrome ... • Urine Chloride ... #syndrome #Bartter ... #Algorithm #nephrology
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... • Gitelman's syndrome ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Algorithm Cl- ... diuretic use, Bartter ... syndrome, Gitelman ... #urine #Algorithm ... #nephrology #differential
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
acid transporter Bartter ... ascending limb Gitelman ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Differential #Table
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Differential Diagnosis Algorithm ... - Diuresis - Bartter ... - Gitelman ... #Pathophysiology ... #Nephrology #Chloride
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