6 results
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Stiff Person Syndrome ... Pathophysiology ... antibody that works ... others (botox, sodium ... #neurology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Algorithm 1) ... renal mechanism 2) ... #Algorithm #nephrology ... #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Diagnosis and Workup ... Repeat the sodium ... Step 2. ... • nephrotic syndrome ... #Algorithm #Nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... Rhabdomyolysis Treatment ... #nephrology #management ... #pathophysiology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
3 questions to work ... 2) Is ADH elevated ... demyelination syndrome ... #management #nephrology ... #sodium
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... Pathophysiology: ... • Urine sodium ... Treatment Overview ... #Hepatology #Nephrology