23 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Renal Tubular Defects ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Pocket Comparison Guide to Heritable Hypertension Syndromes (Secondary Hypertension)

Bartter, Gitelman, Liddle, Primary Aldosteronism, 
GRA (Glucocorticoid Remediable
Pocket Comparison ... Heritable Hypertension Syndromes ... Hypertension) Bartter, Gitelman ... #Comparison #Table ... #Diagnosis #Management
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... ascending limb Gitelman ... tubule Liddle syndrome ... Epithelial #Inherited #Defects ... #Kidney #Nephrology
Aphasia - Pathophysiology and Clinical Findings
Broca's Aphasia - Expressive language impairment: non-Fluent
 - Sensory speech areas
Aphasia - Pathophysiology ... Sensory speech areas ... Contralateral sensory deficits ... #Aphasia #Pathophysiology ... Brocas #Wernickes #neurology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... Pseudo Bartter-Gitelman ... #nephrology #management ... #pathophysiology
Gitelman Syndrome - Management
Treatment includes
 - Electrolyte replacement - K & Mg, preferably Cl salts
Gitelman Syndrome ... - Management Treatment ... Ramesh @SRameshMD #Gitelman ... #Syndrome #Management ... #Treatment #nephrology
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... volume overload Urea ... into ammonium by urease-producing ... Has many side effects ... #hyponatremia #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Severe Cushing syndrome ... tubule reabsorptive defect ... furosemide-like lesion) • Gitelman ... syndrome (defective ... Diagnosis #Causes #nephrology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Urea powder • Induces ... into ammonium by urease-producing ... • Major side effects ... SatyaPatelMD #SIADH #Management ... #hyponatremia #nephrology