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diagnosis rheumatology neurology cerebritis differential erythematosus leukemia lupus myelitis oncology sjogrens systemic tafro thrombocytopenia transverse treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... #CNS #neurology ... cerebritis #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... : CNS manifestations ... • Tumor lysis syndrome ... Intracellular Urate ... #Leukemia #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... • 8%-27% for CNS ... Nephrogenic DI Hematologic ... Diagnosis #Management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... • Infectious causes ... Disorders: - SLE ... Myelitis #diagnosis #management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
erythematosus (SLE ... cell lymphoma Pathophysiology ... histopathologic changes in LNs ... TAFRO #diagnosis #management ... #rheumatology #
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