2 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... (TLS) Tumor Cell ... / Xanthine -> Uric ... Precipitation => • Urate ... #TLS #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... phos, Elevated uric ... , Elevated Cr, Low ... #TLS #diagnosis ... #management #hematology