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diagnosis differential alkalosis chloride defects hypokalemia hyponatremia hypotonic inherited kidney management metabolic physiologic tubule urinary
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
ascending limb Gitelman ... sodium channels ... sodium channels ... Defects #Kidney #Nephrology ... #Differential #Table
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Urinary Chloride Algorithm ... , Gitelman syndrome ... sodium is typically ... the excretion of sodium ... #Algorithm #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... Hypocalciuria (spot urine ... #nephrology #management ... #pathophysiology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
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