5 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... alkalosis • Normal or low ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Algorithm Cl- ... alkalosis • Normal/low ... diuretic use, Bartter ... syndrome, Gitelman ... #nephrology #differential
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Decreased Intake: • Low ... - Diuresis - Bartter ... - Gitelman ... #Pathophysiology ... #Nephrology #Chloride
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
be treated with IV ... Emesis, Diuretics, Bartter ... syndrome, Gitelman ... differential #potassium #nephrology ... #low
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... the blood-brain barrier ... ARVs can have low ... The clinical syndrome ... and with low CD4