18 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Gitelman syndrome ... from Bartter syndrome ... • Urine Chloride ... #syndrome #Bartter ... #Algorithm #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... intake • Metabolic ... thiazide diuretics, Bartter ... syndrome, Gitelman ... #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... #Primary #Metabolic ... #nephrology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... - Normal/low ... diuretic use, Bartter ... syndrome, Gitelman ... syndrome, Hypomagnesemia
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Causes of Metabolic ... Differential Diagnosis Algorithm ... Decreased BP = Bartter's ... Syndrome, Gitelman's ... Syndrome Dr.
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Differential Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... #Nephrology #Causes
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Algorithm Cl- ... alkalosis • Normal/low ... diuretic use, Bartter ... syndrome, Gitelman ... #nephrology #differential
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... alkalosis • Normal or low ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #pathophysiology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... → Hypokalemia Metabolic ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Decreased Intake: • Low ... - Diuresis - Bartter ... - Gitelman ... #Pathophysiology ... #Nephrology #Chloride