23 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Renal Tubular Defects ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... #Pathophysiology ... #Nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Gitelman ... syndrome - ... Genetic defects ... Low #Magnesium #Table ... Classification #Causes
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... ascending limb Gitelman ... Epithelial #Inherited #Defects ... #Kidney #Nephrology ... #Differential #Table
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... volume overload Urea ... into ammonium by urease-producing ... Has many side effects ... #hyponatremia #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... tubule reabsorptive defect ... furosemide-like lesion) • Gitelman ... Differential #Diagnosis #Causes ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... Pseudo Bartter-Gitelman ... #nephrology #management ... #pathophysiology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Urea powder • Induces ... into ammonium by urease-producing ... • Major side effects ... SatyaPatelMD #SIADH #Management ... #hyponatremia #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... iniury, Compartment syndrome ... Dermatomyositis) AKI - Pathophysiology ... per day until stable ... #Summary #causes
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... Self-limiting, chronic but stable ... • Heerfordt syndrome ... Sarcoidosis #Diagnosis #Management
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
disconnection syndrome ... the most common cause ... Pathophysiology: ... Agraphia #clinical #neurology ... #diagnosis #pathophysiology