26 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Algorithm for Differentiating ... Gitelman syndrome ... • Urine Chloride ... • Urine Ca/Cr ... #Algorithm #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Differential Diagnosis Algorithm ... Urine chloride ... diuretic use Urine ... BP = Bartter's Syndrome ... , Gitelman's Syndrome
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Chloride Algorithm ... , Gitelman syndrome ... Urine chloride is ... #Chloride #urine ... #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Differential Diagnosis Algorithm ... hyperaldosteronism • Low Urine ... (late) • High Urine ... , Gitelman Syndrome ... #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Differential Diagnosis Algorithm ... (late) • High Urine ... , Gitelman Syndrome ... #Nephrology #Causes
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... - Urinary Chloride ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... #causes #urinary
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
volume contracted: urine ... volume expanded: urine ... > 20 meq/L • Primary ... furosemide-like lesion) • Gitelman ... Diagnosis #Causes #nephrology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... Uric Acid (low urinary ... Allantoin (High urinary ... Precipitation => • Urate
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... Hypocalciuria (spot urine ... • Congenital chloride ... #nephrology #management ... #pathophysiology