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diagnosis aids alkalosis associated causes dementia differential disorder fanconi hand hiv hypokalemia liddle localization management metabolic nephron neurocognitive neurology
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Renal Tubular Defects ... Proximal tubule Bartter ... #Fanconi #Bartter ... #Pathophysiology ... #Nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... Hypocalciuria (spot urine ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #pathophysiology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
volume contracted: urine ... tubule reabsorptive defect ... actively working • Bartter ... furosemide-like lesion) • Gitelman ... Diagnosis #Causes #nephrology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... (BBB), and infects ... volume • Patchy areas ... The clinical syndrome ... dementia #AIDS #Neurology
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